Method for preparing solution of cisplatine
专利摘要:
There are provided stable concentrated solutions of cisplatin in a solvent comprising polyethylene glycol or methoxy polyethylene glycol, or a mixture thereof, plus water and a nontoxic pharmaceutically acceptable source of chloride ion. 公开号:SU1056893A3 申请号:SU813265697 申请日:1981-03-30 公开日:1983-11-23 发明作者:Артур Каплан Мюррэй;Питер Гранатек Альфонс 申请人:Бристоль-Мейерз Компани (Фирма); IPC主号:
专利说明:
WITH SP ABOUT 00 with 00
权利要求:
Claims (1) [1] * METHOD FOR PRODUCING A CISPLATIN SOLUTION by introducing cisplatin into an aqueous solution containing a pharmaceutically non-toxic source of chloridion, characterized in that, in order to ensure the possibility of obtaining a stable solution containing 2.5-25 mg / ml cisplatin, polyethylene glycol is preliminarily added to the aqueous solution, having a molecular weight of 150-9000 or methoxypolyethylene glycol, having a molecular weight of 300-6000, in the number of st. ve 30-95% of the volume of the solution. Ιω cl 00 with>
类似技术:
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同族专利:
公开号 | 公开日 PT72774A|1981-04-01| DK144281A|1981-10-01| DK158564B|1990-06-11| JPS56152415A|1981-11-26| DK158564C|1990-11-05| ES500869A0|1982-08-16| PT72774B|1982-11-16| ATA150481A|1982-10-15| ZA812084B|1982-04-28| CS246051B2|1986-10-16| ES8206545A1|1982-08-16| GB2074028A|1981-10-28| NO156675B|1987-07-27| KR830004849A|1983-07-20| IE51070B1|1986-09-17| FI810934L|1981-10-01| IL62517D0|1981-05-20| IT1170838B|1987-06-03| IL62517A|1984-01-31| LU83270A1|1981-10-29| CA1162479A|1984-02-21| PH17152A|1984-06-13| DD157762A5|1982-12-08| AR225500A1|1982-03-31| NZ196519A|1983-06-17| AU6816681A|1981-10-08| JPS6360008B2|1988-11-22| FR2480605B1|1984-05-11| GR72769B|1983-12-02| IE810715L|1981-09-30| NL8101531A|1981-10-16| FI70670B|1986-06-26| NO156675C|1987-11-04| DE3112272C2|1990-09-27| NO811081L|1981-10-01| FR2480605A1|1981-10-23| DE3112272A1|1982-04-29| BE888209A|1981-09-30| SE455045B|1988-06-20| CH647481A5|1985-01-31| HU183379B|1984-04-28| KR860000841B1|1986-07-09| FI70670C|1986-10-06| SE8101990L|1981-11-13| AU541056B2|1984-12-13| IT8148090D0|1981-03-24| AT370996B|1983-05-25| GB2074028B|1983-09-21|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题 US4177263A|1972-02-28|1979-12-04|Research Corporation|Anti-animal tumor method| SE445172B|1978-05-30|1986-06-09|Bristol Myers Co|STABLE, STERILE WATER DISPOSAL OF CISPLATIN IN UNIT DOSAGE FORM|IT1153974B|1982-09-23|1987-01-21|Erba Farmitalia|PHARMACOLOGICAL COMPOSITIONS BASED ON CISPLATIN AND METHOD FOR THEIR OBTAINMENT| NL8303657A|1983-10-24|1985-05-17|Pharmachemie Bv|SOLUTION, STABLE, AQUEOUS, AQUEOUS, CONTAINING SOLUTION OF CISPLATINE, AND METHOD OF PREPARING THEREOF.| FI895340A0|1988-11-14|1989-11-09|Squibb Bristol Myers Co|HYPERTONISK CISPLATIN-LOESNING.| AU714992B2|1996-08-23|2000-01-13|Alza Corporation|Liposomes containing a cisplatin compound| AUPQ641100A0|2000-03-23|2000-04-15|Australia Nuclear Science & Technology Organisation|Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents| JP4445304B2|2004-03-26|2010-04-07|オンキヨー株式会社|Switching amplifier| US8852566B2|2009-03-26|2014-10-07|Warsaw Orthopedic, Inc.|Compositions and methods for preferential distribution of active agents to injury sites|
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申请号 | 申请日 | 专利标题 US13537380A| true| 1980-03-31|1980-03-31| 相关专利
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